EternaLift™
Develop next-generation longevity formulations with extracellular vesicles.
Clinically demonstrated probiotic-derived extracellular vesicles for advanced longevity skincare.
Give your formulation a biological advantage.
Today's most advanced skincare isn’t built around trends. It’s built around biology.
EternaLift™ is a clinically demonstrated probiotic-derived extracellular vesicle ingredient developed for formulators creating premium longevity skincare.
A new generation of skin science
Skin ageing is increasingly understood as a decline in cellular communication, barrier function and skin resilience — not simply collagen loss.
As formulation science evolves, extracellular vesicles are emerging as a new generation of bioactive technology, helping formulators work with the biology of the skin rather than simply targeting visible signs of ageing.
Why formulators choose EternaLift™
Not all extracellular vesicles are created equal.
EternaLift™is produced through our proprietary triple-strain probiotic fermentation process, optimised to generate high-quality extracellular vesicles that support intelligent cellular communication.
The result is a clinically demonstrated ingredient developed for formulators seeking advanced performance and a point of difference in longevity skincare.
Designed to perform in the lab as well as on the skin.
✓ Clinically demonstrated — Visible improvements in hydration, elasticity, radiance and wrinkle appearance.
✓ Easy to formulate — Fully water soluble with a recommended use level of 1%.
✓ Premium positioning — Ideal for longevity and microbiome-conscious skincare.
✓ Commercially ready — Vegan & China compliant.
Clinical performance
Clinically evaluated. Statistically significant. Visible results.
In a 28-day split-face clinical study, EternaLift™ delivered statistically significant improvements across every measured endpoint.
Detailed clinical outcomes
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Crow’s Feet Number
Total crow’s feet count reduced 35.9% versus minimal 3.2% control reduction (p = 0.00000000001, paired t-test). Exceptional Cohen’s d = -2.84 represents the study’s strongest treatment effect, confirming clear visible wrinkle reduction.
Crow’s Feet Depth
Average wrinkle depth reduced 7.3% while control showed slight +1.0% deepening (p = 0.006, paired t-test). Cohen’s d = -0.65 indicates moderate but clinically relevant smoothing effect.
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Crow’s Feet Length
Cumulative wrinkle length decreased 31.3% in treated skin versus 4.7% control (p = 0.00008, paired t-test). Cohen’s d= -1.04 confirms large effect size for meaningful line shortening.
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Skin Elasticity/Firmness
Elasticity parameters increased 39.2% in treatment areas compared to 20.6% control improvement (p = 0.00000005, paired t-test). The very large Cohen’s d = 1.77 underscores exceptional firming and structural support performance.
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Stratum Corneum Hydration
Treated sites demonstrated a substantial 36.0% increase in hydration levels while control sites achieved only 12.4% improvement (p = 0.000003, Wilcoxon signed-rank). Cohen’s d = 1.72 confirms large effect magnitude indicating strong, clinically meaningful hydration superiority over control.
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Skin Glossiness/Surface Radiance
Gloss measurement improved by 35.9% in evaBiome eternaLift treated areas versus 17.0% in controls (p = 0.0000006, paired t-test). Cohen’s d = 1.50 reflects large effect size demonstrating significantly enhanced surface smoothness and light reflectance properties. Beneficial in acne-prone skin.
28-day controlled clinical study. 22 participants. 1% inclusion level.
Technical snapshot
INCI: Lactobacillus Ferment
Recommended use level: 1.0%
Appearance: Translucent liquid
Solubility: Fully water soluble
Shelf life: 24 months
Origin: Bioprocessing
Certifications: Vegan • GMO-Free • China Compliant
Applications: Serums • Creams • Eye treatments • Masks • Premium anti-ageing formulations
Complete the formulation
Great formulations consider every ingredient.
An advanced active is only part of the formulation story. Your preservative system also plays a role in the overall formulation.
xoBiome EpiProtect™ was developed to complement microbiome-conscious formulations, helping preserve finished products while supporting the same biology-first philosophy behind EternaLift™.
Ready to formulate with EternaLift™?
Interested in incorporating EternaLift™ into your next formulation?
Contact your local distributor for pricing, technical documentation and commercial enquiries.
For questions about xoBiome EpiProtect™, complete the enquiry form and our ingredient specialists will be in touch.